Hormone Replacement Therapy Lawyer

See below

I've removed references to Wiley. There are at most a few thousand women on the Wiley Protocol, and a few MILLION on other forms of BHRT, and millions more on HRT. Stick to the subject. If you want to malign Wiley, do it on her page. This entries are just an attempt by someone to advance their anti-Wiley agenda in as many places as possible. Neil Raden 23:17, 23 April 2007 (UTC)

The "discussion" below is blatant advertising, which even includes the phone number of the promoter. I don't think that the article itself is advertising. --KeepItClean 23:10, 16 November 2006 (UTC)

POV

While not completely biased, this article does not appear to comply with Wikipedia's policy on Neutral Point of View. The article does not seem to discuss the views of critics of this therapy, and does not put it in context. What is the mainstream medical view of this type of therapy vs. the conventional type?--Srleffler 06:32, 20 November 2006 (UTC)

I find the POV of this article to be clearly biased against mainstream treatments, particularly as it seems to imply that horse derived hormones and "conventional" non-bioidentical hormones are inferior to those used in BHRT, as if bio-identical hormones were hard to obtain except through special treatment programs using individually compounded preparations. Many mainstream treatments use exact copies of human hormones, such as Estrace and Estrogel. Clearly, some providers of so-called BHRT are making great amounts of money, and are trying to protect their financial interests by misrepresenting the availability of exact copies of human estrogens. This situation appears to be affecting the POV of this article. Janice Vian, Ph.D. 137.186.253.216 (talk) 18:59, 18 April 2009 (UTC)

Advertising in Page

Several of the links in the lower body of this article go directly to a site that is selling creams and other items for hormone replacement therapy. The site, hormoneprofiles.com, is essentially using this wiki page as a forward for thier products.

References

I notice that a bunch of references were removed, including the books by Suzanne Somers. While I approve of attempts to clean up the article and reduce POV, I wonder if this went too far. Whatever the merits of her arguments, it seems that Ms. Somers is a notable spokesperson for bioidentical hormone replacement therapy and has written several books promoting it. This probably deserves some mention in the article. Additionally, removal of references should always be handled with some care. If it's possible that some of the material still in the article was drawn from or inspired by her books, they should remain as listed references for the article.--Srleffler 03:28, 4 January 2007 (UTC)

It should also be noted that Wyeth Pharmacueticals, one manufacturer of HRT has filed a "citizen petition" with the FDA over their concern over the use of bioidentical hormones. Wyeth has urged the FDA to stop compounding pharmacies from using estriol in alternative HRT, which many women switched to after the result of the WHI study results. Bioidenticals are cutting into the market share of "big pharma," and they are holding fire to the FDA to pull all other products that may complete with them. The FDA's actions are nothing more than pharmaceutical companies pulling their puppet strings, and, once again, have nothing to do with sciencePharmacy01 (talk) 21:09, 23 January 2008 (UTC)

FDA APPROVAL

In the small caveat posted in this article regarding the FDA status of BHRT treatments, the author suggests that bioidentical hormones are not approved by the FDA and that there is no substantive clinical research suggesting their safety or efficacy. This is patently false. There are, in fact, numerous studies which suggest clinical efficacy of 17-Beta Estradiol in combination with noresthisterone acetate (as opposed to MPA as the active progesterone) - several of which actually demonstrate possible cardiovascular advantages well above that of traditional HRT.

It should also be noted in this article that 17-Beta Estradiol accounts for the vast majority of treatment models used in Europe for HRT in menopausal patients.

On the issue of FDA approval, there are quite a few BHRT products that carry FDA approval... Vivelle, Estrogel, Estrace, Prometrium, etc., all have FDA approval, and, I believe are listed in the Physicians Desk Reference (PDR). Bortsky 15:03, 19 January 2007 (UTC)Bortsky

I see that the "caveat" section has been discussed somewhat here. I hope that debate continues, but, however, also I wanted to let you all know I deleted the current text of the "caveat". The format is not appropriate for the article or an encyclopedia; the information NEEDS to be SYNTHESIZED into the rest of the article. Also, the text must be presented in an unbiased way. The "caveat" cannot act as a disclaimer, cautionary warning before the main text, etc. Please create a section titled "FDA Approval", "Controversy", or something else appropriate. Thanks! JeffreyN 20:28, 29 January 2007 (UTC)

The FDA has issued a warning to several compunding pharmacies, that estriol is not approved for human use, and that the term "bio-identical" is unscientific and misleading. Referrence added to the article. Pustelnik (talk) 12:12, 10 January 2008 (UTC)

Wiley protocol

There's a lot of flack for and against the Wiley protocol, rather than bunging up this page, I created one for it. WLU 19:31, 25 April 2007 (UTC)

72.205.193.253 17:32, 3 May 2007 (UTC)

The Wiley protocol is a type of BHRT, it should be on the page, and if you know of 15-20 other protocols, feel free to add them to the page as well. There is perfect logic to highlighting Wiley here, or at least pointing to the main article. The fact that there is not information about other types of BHRT means the page should be expanded, not truncated. Should you be informed of these other protocols, feel free to add sourced information to the page. Wiley and the Wiley protocol is a well-known type of BHRT because of Somers public, televised advocacy of the protocol, so it is quite natural that there would be considerable interest and more information about it on this page than other types of protocols. WLU 17:15, 6 May 2007 (UTC)

Bioidentical

To the best of my knowledge, there are no commercials by Suzzane Somers promoting BHRT. There have been, I think, commercials promoting her books, but they are episodic with a release. I think this sentence is misleading, as if she is constantly pitching BHRT on television. She talks about it when she is an invited guest. 72.205.193.253 17:38, 3 May 2007 (UTC)

Patents

This article says "Because bioidentical hormones are natural, they are not patentable." Is this true? If it is, a source should be cited. I'm pretty sure there are a large number of natural compounds patented in some way or another...e.g. epo, taq polymerase, etc.

Editor Needed

I am COI so I won't edit this article.However, Suzanne Sommers does NOT promote the Wiley Protocol and is not a spokesperson for it. In the december 2007 issue of Discover magazine, she said, "I do not endorse Wiley. I do not get my hormones from her." I've asked before, but will someone please remove this statement from this article as well as Wiley Protocol and ]. Thank you. Neil Raden (talk) 00:10, 28 January 2008 (UTC)

Estriol

All of the comments in this article about estriol, with the exception of the FDA not approving it, are highly speculative. There are no studies that estriol "protects the breast," only that it binds to ERbeta receptor, which doesn't prove anything. For example, to say that there is no proof that BHRT is safer because there are no long-term clinical trials, then to speculate on the role of estriol based on an observed effect at the molecular level, is just bad science. Estriol (E3) is a spent metabolite of estradiol (E2). If E2 is present in serum at appropriate levels, it is used and estriol results. There is no need to "supplement" it. Please note that estriol is the most widely (biest) used estrogen in compounded BHRT, except the Wiley Protocol, which uses only estradiol. Neil Raden (talk)

support for BHRT

For all those adding evidence in favor of the bioidentical hormones, I suggest using PMID 18928825 which summarizes everything (fulltext here) Mathityahu (talk) 17:07, 8 February 2009 (UTC)

Major Edit

The article has undergone a major re-edit since the comments above were posted.Hillinpa (talk) 12:37, 15 February 2009 (UTC)

recent deletions

This page has been cleared from 40k+ to about 10k in the past few days, after accusation of COATTRACK and SYNTHESIS. While there was possibly a synthesis of many sources, the current content does not reflect at all the many scientific publications that showed the superiority of BHRT compared to traditional (synthetic) HRT. To avoid synthesis but still be loyal to the great amount of evidence in support of BHRT compared to HRT I suggest using the recent publication I referred to above under "support for BHRT". Since it references probably most if not all of the previously deleted references, the entire text can be restored and a reference can be added to this publication. This way it won't be synthesis anymore, since it's all specified in this peer-reviewed publication. Mathityah

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